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CJC-1295 stimulates the pituitary gland to release growth hormone, while Ipamorelin enhances GH secretion through the ghrelin pathway

This type of anemia can cause symptoms such as fatigue, weakness, and shortness of breath

Because growth hormone and insulin counterbalance each other, excess stimulation may lead to insulin resistance, a risk not well studied in peptide use

Indications include: Medically refractory disease not responding to optimized biologic therapy Bowel obstruction from fibrostenotic stricture Intra-abdominal abscess not amenable to percutaneous drainage Complex perianal fistula (seton placement, diversion) Enterocutaneous or enterovesical fistula Dysplasia or cancer in Crohns colitis Free perforation (rare) Nutritional Therapy Exclusive enteral nutrition (EEN) effective for induction in pediatric Crohns

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Meanwhile, vitamin B12 and folic acid supplements have shown promising results among these patients